New Discoveries about Glial Cells (BSP 69)

Recent research has discovered that glial cells (the non-neuronal cells that make up about 85% of the cells in the human nervous system) actually do more than just support neurons. In Episode 69 of the Brain Science Podcast I explore some of these recent discoveries with pioneering researcher, R. Douglas Fields, PhD. Dr. Fields is the author of The Other Brain: From Dementia to Schizophrenia, How New Discoveries about the Brain Are Revolutionizing Medicine and Science. The Other Brain provides a compelling introduction to this exciting new field. It is aimed at general readers, but it should also be on the must-read list for all students of neuroscience.

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"The Myth of Alzheimer's" with Dr. Peter Whitehouse (BSP 68)

Brain Science Podcast 68 is an interview with Dr. Peter Whitehouse, co-author (with Daniel George) of The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis. Alzheimer's Disease originally referred to a relatively rare form of premature dementia, but in recent decades the diagnosis has been expanded to include patients of all ages. This change is not based on science and in this interview we talk about why being labeled with with Alzheimer's may be doing older patients more harm than good. Dr. Whitehouse is one of the pioneering researchers in this field, but advocates devoting resources to helping elders with with a wide range of age-related brain changes. This interview should be of interest to physicians, scientists, as well as patients and their families. I will be posting a supplemental interview with Daniel George, the co-author of The Myth of Alzheimer's later this month. (Learn more at /.)

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Thomas Metzinger explores Consciousness (BSP 67)

The free podcast version of Brain Science Podcast 67 is now available. It is an interview with German philosopher Thomas Metzinger, author of The Ego Tunnel: The Science of the Mind and the Myth of the Self and Being No One. Dr. Metzinger argues that any credible model for how the brain generates the mind must incorporate unusual human experiences, such as so-called out of body experiences (OBE), and psychiatric conditions. In this interview we explore how OBE and virtual reality experiments shed light on how the brain generates the sense of self that characterizes normal human experience. listen-to-audio Listen to Episode 67 Click here for information about Premium Versions Subscribe to the Brain Science Podcast: itunes-badge-30 zunelogo-70 feed-icon32x32 mail-sticker-tiny Click here for detailed show notes and episode transcripts.
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Memory and the Computational Brain with Randy Gallistel (BSP 66)

Episode 66 of the Brain Science Podcast is an interview with Randy Gallistel, PhD, Co-Director of the Rutgers Center for Cognitive Science and co-author (with Adam Philip King) of Memory and the Computational Brain: Why Cognitive Science will Transform Neuroscience. We discuss why read/write memory is an essential element of computation with an emphasis on the animal experiments that support the claim that brains must possess read/write memory. This is significant because current models, such as neural nets, DO NOT incorporate read/write memory in their assumptions about how brains work. It is not necessary to have any background in information theory or computation to appreciate the experiments that are discussed in this episode. Episode 3 and Episode 12 of the Brain Science Podcast provide  background information for this episode. listen-to-audio Listen to Free Podcast Click here for show notes and episode transcripts.
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Jaak Panksepp Explores Animal Emotions (BSP 65)

Episode 65 of the Brain Science Podcast is an interview with Jaak Panksepp, PhD, author of Affective Neuroscience: The Foundations of Human and Animal Emotions. Dr. Panksepp has done pioneering work on the neural origins of emotions. In this interview we discuss how his work challenges some of the common assumptions about emotions and some of the important implications of his discoveries. New listeners may want to go back and listen to Episode 11 for an introduction to the neuroscience of emotion. listen-to-audio Listen to Episode 65
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New iPhone Application is aimed at Brain Science Podcast fans

bsp_120x105 The new Brain Science Podcast application is now available in the iTunes Store. You will need an iPhone or an iPod Touch to use the application but it does offer several useful features:
  • Listen to any episode without downloading it via iTunes*
  • Read episode trancripts right on your iPhone or Touch
  • One click links to the website, email, and the new phone-in line at 206-984-0358.
  • Background play*
*Note: Streaming audio works best with a WiFi connection.
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"Did My Neurons Make Me Do It?" with Warren Brown (BSP 62)

W-Brown-150 Episode 62 of the Brain Science Podcast is an interview with Warren Brown, PhD, co-author (with Nancey Murphy) of Did My Neurons Make Me Do It?: Philosophical and Neurobiological Perspectives on Moral Responsibility and Free Will. This book was discussed in detail back in Episode 53, but this interview gave me a chance to discuss some of the book's key ideas with Dr. Brown. We focused on why a non-reductive approach is needed in order to formulate ideas about moral responsibility that are consistent with our current neurobiological understanding of the mind.

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Allen Institute for Brain Research (BSP 61)

Allan Jones, PhD
Allan Jones, PhD
Episode 61 of the Brain Science Podcast is an interview with Allan Jones, PhD, the Chief Science Officer of the Allen Institute for Brain Research in Seattle, Washington. The Allen Institute is a non-profit research organization founded by Paul Allen (co-founder of Microsoft) and is best known for its Mouse Brain Map, which is being used by researchers around the world. The Institute has several other on-going projects including a project to create a map of the human cortex that shows which genes are active in each area. In this interview we discuss both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research. All the maps created by The Allen Institute are freely available on the internet. Dr. Jones also shares his own story and the challenges and rewards of pursuing a career in the non-profit biotech world.

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The Importance of Play (BSP 60)

In Episode 60 of the Brain Science Podcast Ginger Campbell, MD interviews Dr. Stuart Brown, author of Play: How It Shapes the Brain, Opens the Imagination, and Invigorates the Soul. Our focus is on the importance of play for normal mental development and psychological health. We also explore the importance of play in adults.

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Guy Caldwell, PhD on C. elegans (BSP 59)

BSP-logo-75-thumb2.jpgEpisode 59 of the Brain Science Podcast is an interview with Dr. Guy Caldwell who is a molecular biologist at the University of Alabama. Since moving to Alabama ten years ago he has done groundbreaking work in applying the green florescent protein techniques developed by his mentor, Nobel Laureate Martin Chalfie to the study of dopamine neurons in the tiny worm C. elegans. In this interview Dr. Campbell and Dr. Caldwell discuss the growing role of molecular biology as a tool in neuroscience. Dr. Caldwell explains why he thinks there is a good chance that a cure for Parkinson's Disease will be found within the next 10 years.

This interview also contains practical information for students interested in pursuing a career in science.

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Neurophsychologist Chris Frith, PhD (BSP 57)

frith Episode 57 of the Brain Science Podcast is an interview with neuropsychologist Dr. Chris Frith, author of Making up the Mind: How the Brain Creates Our Mental World. Our brain processes information about the world outside us (via our senses) in the same way that it processes information from within our bodies and from our own mental world. In this interview Dr. Frith and I explore the implications from recent discoveries about how our brain generates our mental world.

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Pioneering Neuroscientist Eve Marder, PhD (BSP 56)

evemarder2 Episode 56 of the Brain Science Podcast is an interview with neuroscientist, Eve Marder, PhD. Dr. Marder has spent 35 years studying the somatogastric ganglion of the lobster. In this interview we talk about how she got into neuroscience during its early days, her recent tenure as president of the Society for Neuroscience, and how some of her key discoveries have implications for studying more complex nervous systems.

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Philosopher Patricia Churchland (BSP 55)

bsp-300-hi Episode 55 of the Brain Science Podcast is an interview with highly respected philosopher Patricia Churchland. Churchland is the author of Neurophilosophy and Brain. She is currently on the faculty of the University of California at San Diego and she was a featured speaker at the annual meeting of the Society for Neuroscience in 2008. In this interview we talked about neurophilosophy, which is an approach to philosophy of mind that gives high priority to incorporating the empiric findings of neuroscience. We also talk about the evolving relationship between philosophy and neuroscience. Churchland shares her enthusiasm for how the discoveries of neuroscience are changing the way we see ourselves as human beings. We also talked a little about the issues of reductionism that I first brought up in Episode 53.

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Dr. Michael Merzenich on Brain Plasiticity (BSP 54)

bsp-300-hi Brain Science Podcast #54 is an interview with Dr. Michael Merzenich, one of the pioneers of neuroplasticity. We talk about how the success of the cochlear implant revealed unexpected plasticity in adult brains and about how brain plasticity can be tapped to improve a wide variety of problems including dyslexia, autism, damage from disease and injury. Healthy people of all ages can also tap the resource of brain plasticity to help maintain and improve their mental functions.

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Neuroscience and Free Will (BSP 53)

bsp-300-hi Episode 53 of the Brain Science Podcast is a discussion of Did My Neurons Make Me Do It?: Philosophical and Neurobiological Perspectives on Moral Responsibility and Free Will by Nancey Murphy and Warren S. Brown. This book challenges the widespread fear that neuroscience is revealing an explanation of the human mind that concludes that moral responsibility and free will are illusions created by our brains. Instead the authors argue that the problem is the assumption that a physicalist/materialistic model of the mind must also be reductionist (a viewpoint that all causes are bottom-up). In this podcast I discuss their arguments against causal reductionism and for a dynamic systems model. We also discuss why we need to avoid brain-body dualism and recognize that our mind is more than just what our brain does. The key to preserving our intuitive sense of our selves as free agents capable of reason, moral responsibility, and free will is that the dynamic systems approach allows top-down causation, without resorting to any supernatural causes or breaking any of the know laws of the physical universe. This is a complex topic, but I present a concise overview of the book's key ideas.

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Brain Science Podcast Celebrates its 2nd Anniversary (BSP 52)

gin-bud08-100 Brain Science Podcast #52 is our Second Annual Review Episode. We review some of the highlights from 2008. I also discuss the various other on-line resources that I have created for listeners. Then we look ahead to what I have planned for 2009. This episode is aimed at all listeners, including those who are new to the show.

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